The relationship between number and size of uterine fibroids and perinatal outcome / 中国基层医药

ABSTRACT

Objective To estimate the impact of sonographically identified multiple or large (≥5cm in diameter)fibroids on perinatal outcomes.Methods Retrospective cohort study of 219 women with uterine fibroids was conducted.Results Compared to women with no fibroids,women with multiple fibroids (n =34)had a signifi-cantly higher rate of preterm birth (29.4% vs.5.0%,χ2 =23.0,P <0.001),cesarean section (73.5% vs.37.0%,χ2 =16.0,P <0.001)and breech presentation (11.8% vs.2.7%,χ2 =6.3,P =0.04).Women with large fibroids (n =48)had a higher rate of preterm birth (16.7% vs.5.0%,χ2 =8.1,P =0.01 )and pPROM (10.4% vs. 0.5%,χ2 =17.8,P <0.001).Conclusion Women with uterine fibroids are at increased risk of obstetric complica-tions.Multiple fibroids are associated with a significantly increased risk of preterm birth and cesarean delivery,while large fibroids are associated with a higher risk of pPROM.No correlation with IUGR,placenta previa or placental abruption was found.