Morphological analysis of autophagy / 药学学报
Acta Pharmaceutica Sinica
;
(12): 39-44, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-505088
ABSTRACT
Autophagy is an important homeostatic cellular recycling mechanism responsible for degrading injured or dysfunctional subcellular organelles and proteins in all living cells. The process of autophagy can be divided into three relatively independent steps:
the initiation of phagophore, the formation of autophagosome and the maturation/degradation stage. Different morphological characteristics and molecular marker changes can be observed at these stages. Morphological approaches are useful to produce novel knowledge that would not be achieved through other experimental methods. Here we summarize the morphological methods in monitoring autophagy, the principles in data interpretation and the cautions that should be considered in the study of autophagy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2016
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS