Clinical features of Choroidal Neovascularization in Patient with High Myopia

ABSTRACT

PURPOSE: To investigate the clinical features and ICGA findings of choroidal neovascularization(CNV) in patients with high myopia which could be one of the important causes of CNV. METHODS: We performed FAG and ICG angiography in 21 high myopic patients(23 eyes) with CNV and investigated the visual acuity, associated retinal findings, and treatment modality. RESULTS: The locations of CNV were extrafoveal in 6 eyes(26.1%), juxtafoveal in 13 eyes(56.5%), and subfoveal in 4 eyes(17.4%). All cases of CNV were less than 1 disc diameter in size. On ICG angiography, CNV was better visible in late phase in 8 out of 23 eyes(34.8%) and 5 eyes(21.7%) had better fluorescence in early phase. In 7 eyes(30.4%), CNV was evident only in late phase. In 3 eyes(13.1%), CNV was very poorly visible with ICG angiography in both phases. Final visual acuity was improved in 4 eyes(17.4%), decreased in 6 eyes(26.1%), and unchanged in 13 eyes(56.5%). CONCLUSION: CNV in high myopia was small in size and located mostly in foveal area. ICG angiography showed CNV with different angiographic patterns, but most cases of CNV had better fluorescence in late phase. The visual prognosis was relatively good.