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Relationship between IFN-γ+874 A/T site and IL-2-330 T/G site single nucleotide polymorphism with the susceptibility of recurrent aphthous ulcer / 实用口腔医学杂志
Journal of Practical Stomatology ; (6): 852-856, 2016.
Artículo en Chino | WPRIM | ID: wpr-506236
ABSTRACT

Objective:

To explore the possible relationship between recurrent aphthous ulcer( RAU) and the single nucleotide polymor-phism(SNP)of IFN-γ+874A/T site and IL-2-330T/G site.

Methods:

138 RAU patients and the 124 health control subjects were in-cluded. IFN-γand IL-2 serum concentration were detected by ELISA. IFN-γ+874A/T site and IL-2-330T/G site of the whole blood were detected by RFLP-PCR and SSP-PCR.

Results:

IFN-γand IL-2 levels in serum of the patients were significantly lower than those of the controls(P0. 05).

Conclusion:

IFN-γ+874A/T site was associated with the risk of RAU. But,IL-2-330T/G site was not.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Practical Stomatology Año: 2016 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Practical Stomatology Año: 2016 Tipo del documento: Artículo