Analysis of the Efficacy of Low-dose Progesterone Injection Combined with Baotai Wuyou Capsule in the Treatment of Threatened Abortion / 中国药房

ABSTRACT

OBJECTIVE:To observe the efficacy and safety of low-dose Progesterone injection combined with Baotai wuyou capsule in the treatment of threatened abortion. METHODS:107 patients with threatened abortion were retrospectively analyzed and divided into observation group(54 cases)and control group(53 cases)by different medication. All patients received bed rest orally taking folic acid and other measures. Meanwhile,control group was given Progesterone injection 20-40 mg,qd,intramuscu-larly injected. Observation group was given Progesterone injection 10-20 mg,qd,intramuscularly injected and given 4 Baotai wuy-ou capsule additionally,tid,taking with ginger decoction,no fish during the medication. The courses of 2 groups were 14 d. Clini-cal efficacy,hemostatic time,remission time of abdominal pain and backache in 2 groups were observed,and the incidence of ad-verse reactions during the treatment was recorded. RESULTS:The total effective rate in observation group was significantly higher than control group,hemostatic time,remission time of abdominal pain and backache were significantly shorter than control group, the incidence of adverse reactions was significantly lower than control group,with statistical significances (P<0.05). CONCLU-SIONS:Low-dose Progesterone injection combined with Baotai wuyou capsule shows good efficacy in the treatment of threatened abortion,which can shorten patients'hemostatic time,remission time of abdominal pain and backache,and reduce the incidence of adverse reactions,with good safety.