Spasmodic torticollis: medical and botulinum A toxin treatment
Yonsei Medical Journal
;
: 289-293, 1992.
Artículo
en Inglés
| WPRIM
| ID: wpr-50769
ABSTRACT
The exact pathophysiologic mechanisms of spasmodic torticollis and other idiopathic torsion dystonias remain largely unknown. Thus, a variety of drugs have been used alone or in combination on an empirical basis to treat these disorders, but to date none have efficacy that is proven and consistent. The drugs in use include anticholinergics, benzodiazepines, dopaminergics and dopamine antagonists with variable degrees of clinical improvement. Botulinum toxin A injection treatment for spasmodic torticollis is safe and efficacious with minimal adverse effect. However, it is expensive and beneficial effects are short-lasting. Only when a spasmodic torticollis patient's symptoms are refractory to combined treatment, using various drugs and Botulinum toxin injections, should the patient be considered a candidate for neurosurgical procedures.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Parasimpatolíticos
/
Espasmo
/
Tortícolis
/
Benzodiazepinas
/
Toxinas Botulínicas
/
Dopaminérgicos
/
Antagonistas de Dopamina
Límite:
Humanos
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
1992
Tipo del documento:
Artículo
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