A Case of ANA-negative, Anti-dsDNA Negative, and Anti-Ro/SSA Positive Membranous Lupus Nephropathy
Journal of Rheumatic Diseases
; : 127-131, 2013.
Article
en Ko
| WPRIM
| ID: wpr-50809
Biblioteca responsable:
WPRO
ABSTRACT
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of diverse autoantibodies with various systemic organ involvements. In patients with SLE, autoantibodies, such as antinuclear antibody (ANA) and anti-dsDNA antibody, play an important role not only in diagnosing the disease, but also representing the pathogenesis of the disease. ANA is the main screening tool in diagnosis and serum complement levels and anti-dsDNA antibody level are closely related to the disease activities. Nevertheless, exceptionally, some patients represent with negative ANA and/or anti-dsDNA antibody leading to difficulties in diagnosing the disease. Here, we report a case of 37-year old female SLE patient with negative ANA, negative anti-dsDNA antibody, and positive anti-Ro/SSA antibody, which manifested with nephrotic syndrome.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Autoanticuerpos
/
Enfermedades Autoinmunes
/
Proteínas del Sistema Complemento
/
Glomerulonefritis Membranosa
/
Tamizaje Masivo
/
Anticuerpos Antinucleares
/
Lupus Eritematoso Sistémico
/
Síndrome Nefrótico
Tipo de estudio:
Prognostic_studies
/
Screening_studies
Límite:
Female
/
Humans
Idioma:
Ko
Revista:
Journal of Rheumatic Diseases
Año:
2013
Tipo del documento:
Article