Cyclophosphamide-induced Posterior Reversible Encephalopathy Syndrome in a Patient with Lupus Nephritis
Journal of Rheumatic Diseases
;
: 103-107, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-50814
ABSTRACT
Posterior reversible encephalopathy syndrome (PRES) is a neurologic condition characterized by vasogenic edema on neuroimaging and is associated with the setting of severe hypertension, eclampsia, autoimmune disease, malignancy, and immunosuppressive drugs. We report on a 42 year-old female systemic lupus erythematous patient who presented altered consciousness, seizure, and visual disturbance after cyclophosphamide pulse therapy. Magnetic resonance imaging (MRI) showed multi-focal high signal intensity lesions in the parieto-occipital cortex bilaterally and in the subcortical white matter. Her condition was improved and her MRI lesions were resolved after aggressive blood pressure control and high-dose steroid treatment. It is possibly the first reported case of PRES in a patient with lupus, treated with cyclophosphamide pulse therapy during a nephritis flare in Korea.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Convulsiones
/
Enfermedades Autoinmunes
/
Presión Sanguínea
/
Nefritis Lúpica
/
Imagen por Resonancia Magnética
/
Estado de Conciencia
/
Ciclofosfamida
/
Eclampsia
/
Edema
/
Neuroimagen
Límite:
Femenino
/
Humanos
/
Embarazo
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Journal of Rheumatic Diseases
Año:
2013
Tipo del documento:
Artículo
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