Influence ofFurong-Tongmai capsules on myocardial expression of LN and CollagenⅢ in diabetes mellitus rats / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
; (6): 140-143, 2017.
Article
en Zh
| WPRIM
| ID: wpr-508198
Biblioteca responsable:
WPRO
ABSTRACT
Objective To explore the the influence ofFurong-Tongmai capsules on myocardial expression of LN and CollagenⅢ in diabetes mellitus (DM) rats.Methods A total of 60 rats were randomly divided into the control group, the model group, the low-, middle- high-dosageFurong-Tongmai capsules group (n=10). The low-, middle-high-dosageFurong-Tongmai group was given 1.4, 0.7, 2.8 g/(kg body weight) Furong-Tongmai capsules. The other two groups were given the same dose of purified water. After 8 weeks treatment, the myocardial was taken to make pathology slice with SP immunohistochemistry staining. The expression of LN and CollagenⅢ were detected.Results Compared with model group, the expression of LN (0.67% ± 0.04%,0.65% ± 0.09%vs. 1.08% ± 0.13%) and CollagenⅢ (0.67% ± 0.15%, 0.69% ± 0.13%vs. 1.17% ± 0.12%) in the middle-high-dosageFurong-Tongmai groups significantly decreased (P0.05).Conclusions TheFurong-Tongmai capsules could inhibit the expression of LN and CollagenⅢ in DM rats.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
International Journal of Traditional Chinese Medicine
Año:
2017
Tipo del documento:
Article