Analysis of the Patients with Indeterminate Results by Anti-HIV Western Blot Assay: Experience of a University Hospital During Recent 5 Years in Korea / 임상검사와정도관리
Journal of Laboratory Medicine and Quality Assurance
;
: 49-55, 2011.
Artículo
en Coreano
| WPRIM
| ID: wpr-50878
ABSTRACT
BACKGROUND:
Interpretation of indeterminate results by anti-HIV Western blot assay, which is currently used as a confirmatory test for HIV infection, can be usually difficult. We analyzed outcomes of the patients with indeterminate results by anti-HIV Western blot.METHODS:
Medical records of patients, who were indeterminate by the anti-HIV Western blot assay in a university hospital during recent 5 years, were retrospectively reviewed. HIV screening test was performed by chemiluminescent immunoassay autoanalyzer (Abbot Laboratories, USA) with HIV Ag/Ab Combo kits. Confirmatory Western blot assay for the positive samples by HIV screening test was committed to the Korean National Institute of Health.RESULTS:
A total of 202,639 specimens were tested for HIV screening during the period, and 644 (0.32%) sera showed positive results. Among these, 46 (7.1%) cases were indeterminate by the Western blot, which were from 20 patients, and 13 of them converted to be anti-HIV positive, and 3 were lost to follow-up. Another four patients were turned out to be negative for HIV infection, including two neonates from HIV-positive mothers receiving antiviral treatment during pregnancy.CONCLUSIONS:
Most of the patients who showed Western blot-indeterminate results converted to HIV positive after follow-up. Thus, careful monitoring of patients with indeterminate Western blot results should be essential.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Inmunoensayo
/
Infecciones por VIH
/
Tamizaje Masivo
/
Registros Médicos
/
Western Blotting
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
VIH
/
Perdida de Seguimiento
/
Corea (Geográfico)
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Humanos
/
Recién Nacido
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Journal of Laboratory Medicine and Quality Assurance
Año:
2011
Tipo del documento:
Artículo
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