A Case of Metastatic Small Cell Neuroendocrine Carcinoma of the Lung Mimicking a Merkel Cell Carcinoma / 대한피부과학회지
Korean Journal of Dermatology
;
: 774-779, 2003.
Artículo
en Coreano
| WPRIM
| ID: wpr-50967
ABSTRACT
Metastatic small cell neuroendocrine carcinomas(MSCNC) from distant sites, such as the lung, are high grade tumors with poor prognosis. Histopathologically, it is difficult to distinguish between MSCNC and Merkel cell carcinoma solely on the basis of histologic morphology, electron microscopy, and immunohistochemistry. In recent years, differential expression of cytokeratin(CK) 20 and thyroid transcription factor(TTF)-1 has been proposed as useful distinguishing features. It must be emphasized that clinical correlation(e.g. symptomatology, chest X-ray) and a combination of CK 20 and TTF-1 markers, are essential to differentiate these two disease entities. We herein present a case of MSCNC of the lung that might be misdiagnosed as Merkel cell carcinoma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Tórax
/
Glándula Tiroides
/
Inmunohistoquímica
/
Microscopía Electrónica
/
Carcinoma de Células de Merkel
/
Carcinoma Neuroendocrino
/
Pulmón
Tipo de estudio:
Estudio pronóstico
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2003
Tipo del documento:
Artículo
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