Chaihu Shugan decoction combined with Group cognitive behavioral therapy on effect of HAMD and NIHSS in patients with depression after stroke / 中国生化药物杂志

ABSTRACT

Objective To investigate the Chaihu Shugan decoction combined with Group cognitive behavioral therapy on curative effect and neurologic impairment in patients with depression after stroke. Methods 80 PSD patients were randomly divided into our hospital encephalopathy rehabilitation were selected as control group and observation group, 40 cases in each group. The routine drug treatment and rehabilitation training for all patients with Deanxit tablet. The observation group added ChaiHuShuGan Decoction and group cognitive behavioral therapy in the control group based on the treatment. Two groups of patients with 24h before treatment and after 8 weeks of treatment, the Hamilton Depression Scale, the degree of neural function defect scale and evaluation index of Basel. Results After 8 weeks treatment, the total effective rate of the observation group was 95% (38 / 40), and the control group was 75% (40/30), the difference was statistically significant (P<0.05). The improvement of HAMD, NIHSS and BI scores in the observation group were significantly better than those in the control group, the difference was statistically significant (P<0.05). Conclusion ChaiHuShuGan Decoction has synergistic effect with Group cognitive behavioral therapy in the treatment of PSD can significantly improve the symptoms of depression and neurologic impairment, and can improve the quality of life of patients.