Analgesic effects of 0.15% ropivacaine for the breakthrough pain during labor after epidural analgesia / 临床麻醉学杂志

ABSTRACT

Objective To compare the analgesic effects for breakthrough pain after epidural la-bor analgesia during vaginal delivery by different concentrations of ropivacaine with or without sufen-tanil.Methods A total of 60 full term nulliparous women with singleton (ASA physical status Ⅰ orⅡ)were included,who received successful epidural labor analgesia and experienced breakthrough pain during the first labor phrase.They were randomized into group A (n = 30)and group B (n =30),rescue dose with 0.1 5% pure ropivacaine and 0.08% ropivacaine plus sufentanil 0.4 μg/ml,re-spectively.The VAS score,modified Bromage score,boluses of rescue dose,consumption of analge-sics and oxytocin,durations of labor phrase,modes of labor,and side effects during labor were ob-served.Results Compared with group B,the VAS score 20 min after rescue dose for the break-through pain,the frequency of rescue,the dosage of sufentanil and the incidence of side effects such as itching and urine retention were significantly decreased in group A.Modified Bromage score was 0 in each group. The cases using oxytocin, labor time and childbirth way were similar. Conclusion Rescue dose of 0.1 5% ropivacaine can provide better analgesic effect than those of 0.08% ropivacaine plus sufentanil 0.4 μg/ml for the breakthrough pain during the first labor phrase, with less side effects and higher satisfaction scales.