Antioxidant, anti-alpha-glucosidase and pancreatic beta-cell protective effects of methanolic extract of Ensete superbum Cheesm seeds
Asian Pacific Journal of Tropical Biomedicine
;
(12): 121-125, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-511480
ABSTRACT
Objective:
To investigate the antioxidant, anti-a-glucosidase and pancreatic b-cell protective potential of Ensete superbum (E. superbum) seeds.Methods:
A variety of in vitro assays including radical scavenging, reducing power potential, phenolic content determination, a-glucosidase assay and pancreatic b-cell (1.4E7 cells) viability were employed for assessing the effect of methanolic extract of E. superbum seeds.Results:
The radical scavenging and reducing power effects comparable with the stan-dard rutin were obtained while the enzyme inhibitory activity of the extract was 68-fold better than the standard antidiabetic drug, acarbose. The seed extract of E. superbum was packed-full of polyphenols with mean percentage gallic acid equivalent value of (38.2 ± 1.8) (n = 3). The protection of pancreatic cells from massive onslaught of hydrogen peroxide was far superior to that obtained for rutin.Conclusions:
The reputed antidiabetic therapeutic uses of the seeds extract of E. superbum may be justified on the basis of inhibition of carbohydrate enzymes, anti-oxidant effects and pancreatic b-cell protection.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Asian Pacific Journal of Tropical Biomedicine
Año:
2017
Tipo del documento:
Artículo
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