A Case of Acute Promyelocytic Leukemia with Co-existence of BCR-ABL1 and PML-RARA Rearrangements Detected by PCR
Laboratory Medicine Online
; : 196-200, 2017.
Article
en Ko
| WPRIM
| ID: wpr-51169
Biblioteca responsable:
WPRO
ABSTRACT
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) characterized by PML-RARA fusion and specific morphology. The BCR-ABL1 rearrangement is mainly observed in patients with chronic myeloid leukiemia (CML). However, it is also found in patients with acute lymphoblastic leukemia (ALL) and in a few patients with AML. However, it is very rarely observed in patients with APL. Here, we report a case of APL with t(15;17) and co-existence of PML-RARA and BCR-ABL1. Further study with more cases is warranted to find the right treatment and prognostic significance.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Leucemia Mieloide Aguda
/
Leucemia Promielocítica Aguda
/
Reacción en Cadena de la Polimerasa
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
Límite:
Humans
Idioma:
Ko
Revista:
Laboratory Medicine Online
Año:
2017
Tipo del documento:
Article