Analysis on changes of drug resistance and class Ⅰ integron in clinically isolated Pseudomonas aeruginosa during 2013-2015 / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 886-889, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-512689
ABSTRACT
Objective To investigate the changes of drug resistance and class Ⅰ integron in clinically isolated Pseudomonas aeruginosa(PA) in our hospital form January 2013 to December 2015.Methods Clinically isolated PA strains were divided into the 3 time periods of 2013,2014 and 2015.Their resistance to 22 commonly used antibacterial drugs was investigated by adopting the VITEK-2;200 strains were randomly selected from the isolated strains during these 3 time periods.Class Ⅰ integron was detect by PCR.Results The detected PA in these 3 time periods had 366,437 and 520 strains respectively.The drug resistance of Pseudomonas aeruginosa to 22 commonly used antibacterial drugs was remarkably increased(P<0.05),especially in ICU.The detection rate of class Ⅰ integron positive bacteria was gradually increased year by year,moreover the drug resistance rate of class Ⅰ integron positive bacteria was significantly higher than that of class Ⅰ integron negative bacteria (P<0.01).Conclusion The drug resistance rate of PA in this hospital is higher.The proportions of multi-drug resistance and classⅠ integron are significantly increased.The hospital infection detection and drug-resistant bacterial monitoring should be strengthened to further standardize the use of antibacterial drugs.
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
International Journal of Laboratory Medicine
Año:
2017
Tipo del documento:
Artículo
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