Significance of Hypoxia-related microRNA for Estimating the Cause of Mechanical Asphyxia Death / 法医学杂志

ABSTRACT

U nder hypoxia condition, m icroR N A (m iR N A ) can interact w ith transcription factors for regu-lating the cell m etabolism , angiogenesis, erythropoiesis, cellular proliferation, differentiation and apoptosis. T he biological processes above m ay play an im portant role in m echanical asphyxia death. T his article re-view s the regulating function of m iR N A under hypoxia condition and the influence of hypoxia to biosynthesis of m iR N A , w hich m ay provide som e new ideas to the research of m iR N A on determ ining the cause of m echanical asphyxia death in the field of forensic m edicine.