A preliminary study of the mechanism and therapeutic effect in four types of immunic diseases with plasmapheresis / 中国病理生理杂志

ABSTRACT

This paper presents plasma exchange(P.E) therapy in 8 cases of four types of immunic diseaes. The colony forming unit-T lymphocyte (TL-CFU), the symbol T-cell subsets with monoclone antibody (McAb), and the cisrculating immune complex (CIC)were examined before and after the therapy of P.E. and compared with the interelationship of each other. The experiments indicated that plasmapheresis may remove the CIC and noxious autoantibodies and regulation of the action of cellular immunity. All these functions are synthetic therapeutic effects. The indices of checkup on therapeutics were TL-CFU, CIC and the ratio of T_H and T_S. After plasmaphersis, the ratio of CIC was lowered but the TL was higer than before (P