Effects of GvHR in the pathogenesis of immunologically mediated aplastic anemia in mice / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Artículo
en Chino
| WPRIM
| ID: wpr-516182
ABSTRACT
Using observation of the gross and histological changes of skin, intestine, liver and spleen, the spleen index, the popliteal lymph node weight gaining, and the ~(125)I-UdRincorporation assay, the effects of GvHR in the pathogenesis of immunologically mediatedaplastic anemia in mice were studied. Rtsults showed that there were no gross and histological changes due to GvHR foundin skin, intestine, liver and spleen, and the spleen index decreased markedly, and therewere positive popliteal lymph node weight gaining and positive ~(125)I-UdR incorporationassay which showed a dose dependent corrlation. These results suggested that, transfusion of DBA/2 lymphocytes into lethally irradia-ted BALB/c mice could evoke GvHR, but on the other hand, the effects of GvHR werenot very important in the pathogenesis of immunologically mediated aplastic anemia inmice.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio de etiología
Idioma:
Chino
Revista:
Chinese Journal of Pathophysiology
Año:
1986
Tipo del documento:
Artículo
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