Preliminary Study on the Expression of C-myc Protooncogene in SLE Patients / 中华皮肤科杂志
Chinese Journal of Dermatology
;
(12)1995.
Artículo
en Chino
| WPRIM
| ID: wpr-516347
ABSTRACT
By means of cell hybridization in situ with digoxigenin labeled probe, we detected the expression of C-myc protooncogene in peripheral blood mononuclear cells from 31 SLE patients and 10 healthy persons. The results showed that the level of C-myc mRNA in SLE patients was significantly higher than that in normal controls, and the increased level correlated with disease activity. There was also a positive correlation between C-myc mRNA and serum levels of ANA, anti-dsDNA, IgG, C3. Our study indicates that C-myc gene is important for the pathogenesis of SLE.
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Dermatology
Año:
1995
Tipo del documento:
Artículo
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