The Study of Neuro-immune Protein and the Lymphocyte Transformation in Psoriatic Serum / 中华皮肤科杂志

ABSTRACT

Objective To find out the material base of the induction and aggravation of psoriasis by psycological factors such as stress and depression etc. Methods Radioimmunoassay (RIA) was used to determine the effect of sera from 49 psoriatic patients and 34 healthy controls on the suppression of the lymphocyte transformation of normal mouse lymphocytes. Results The lymphocyte transformation rate of mouse lymphocytes treated with the sera of psoriatic patients was 41.55%, and that of controls was 68.09%. The suppressive effect of sera in patients during the progressive stage and with more extensive lesions were stronger than that in the stable stage and with less lesions (P