Continuous flow apneic ventilation with nitrous oxide-oxygen or oxygen in dogs / 中华麻醉学杂志

ABSTRACT

To investigate the difference of CO_2 transport during continuous flow apneic ventilation (CFAV) between with 100% 0_2 and with 60%N_2O-40% O_2. Method: Twelve dogs were randomly divided into equally group N_2O and group O_2. A catheter was introduced into each main-stem bronchus using a fiberoptic bronchoscope and endotraeheal tube positioned in place for CFAV. With 60%N_2O-40% O_2 in group N_2O and 100% O_2 in group O_2 lungs were ventilated at flow rate of 1L?kg~(-1)?min~(-1) Blood gas analysis, HR, MAP and SaO_2 were recorded every 30min during period of 180min. Result: In group O_2, PaCO_2 increased from 4.88?0.63kPa to 8.73?1.11kPa. In Group N_2O, PaCO_2 were increased gradually from 5.51?0.94kPa to 6.18?0.67kPa. There was significant difference in PaCO_2 between the two groups (P