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The Inhibitory Effect of Dihydro-?-erythroidine on Nicotine Induced-current in Cultured Sympathetic Neurons / 中国药房
China Pharmacy ; (12)1991.
Artículo en Chino | WPRIM | ID: wpr-517420
ABSTRACT

AIM:

To investigate the inhibitory effect of dihydro-?-erythroidine on nicotine induced-current in cultured superior cervical ganglion of neonatal rats.

METHODS:

Pneumatic pressure administration of drug and whole-cell recording techniques were performed to compare induced-current amplitude.

RESULTS:

Dihydro-?-erythroidine competitively antagonized nicotinic effect,and EC50 was about 0.015mmol/L.

CONCLUSION:

Dihydro-?-erythroidine is a competitive antagonist of nicotinic receptors in sympathetic neurons.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: China Pharmacy Año: 1991 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: China Pharmacy Año: 1991 Tipo del documento: Artículo