Clinical and endoscopic features of gastric MALT lymphoma / 中华消化内镜杂志

ABSTRACT

Objective To study the clinical and endoscopic features of Gastric mucosa－ associated lymphoid tissue(MALT) lymphoma. Methods Clinical and endoscopic data of thirty two patients with gastric MALT lymphoma diagnosed pathologically after opration were analyzed. Results Patients with gastric MALT lymphoma had a median age of 51.3years with male predominance and a bimodal age distribution pattern, aged 30～ 39 and 60～ 69 years respectively. The symptoms were not characteristic.The tumor originated from antrum in 12 cases,corpus in 8 and multifocal lesions were found in 12 instances. The tumor appeared infilitrative in 12, ulcerative in 16 and nodular in 6 patients endoscopically. Lymphatic metastasis was detected in infiltrative type, before the serosa was involved. Immunohistochemistry showed B－ cell lymphoma in all the 32 cases.And Helicobacter pylori(H.pylori) infection was found in 27 cases(84.4％ ).Nocorrelation was found between endoscopic types and manifestations.Metastasis to local lymph nodes was found early in infiltrative tumor.Conclusions It is suggested that H.pylori infection may play a role in the pathogenesis of gastric MALT lymphoma.