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Effect of intestinal endotoxemia on hepatic energy metabolism in acute liver failure / 中国病理生理杂志
Chinese Journal of Pathophysiology ; (12)1999.
Artículo en Chino | WPRIM | ID: wpr-518120
ABSTRACT

AIM:

To study the effect of intestinal endotoxemia(IETM) on hepatic energy metabolism in acute liver failure.

METHODS:

Intoxication by thioacetamide (TAA) was used to establish rat model of acute liver injury.Ketone body(acetoacetate and ?-hydroxybutyrate) in arterial blood and ATP content of hepatocellular mitochondria were determined by using enzymatic fluorimetric micromethod.Colectomy was adopted in observing the changes in plasma endotoxin content and serum alanine aminotransferase (ALT) activity.

RESULTS:

In the TAA group,plasma endotoxin content and serum ALT activity were all significantly higher than those in the control group(P

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Pathophysiology Año: 1999 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Pathophysiology Año: 1999 Tipo del documento: Artículo