Effect of PKC activition on cardiac myocyte apoptosis and Bcl-2 expression during myocardial ischemia/reperfusion in rats / 中国病理生理杂志

ABSTRACT

AIM: To explore the effect of PKC activition on cardiac myocyte apoptosis and expression of bcl-2 during myocardial ischemia/reperfusion(I/R) in rats. METHODS: TUNEL,immunohistochemistry and in situ hybridization were used. RESULTS: The TUNEL data showed that the numbers of positive cardiac myocyte nucleus and the percentage of positive cardiac myocyte nucleus in PMA+IR 3 h group decreased significantly( P