Study on Mechanism of Action of Compound Huanggan Granules on the Kidney / 中国药房

ABSTRACT

OBJECTIVE:To research the mechanism of action of compound Huanggan gr anules(FHG) METHODS:To observe the effect of FHG on the renal blood flow and glomerular filtration rate,and its mechanism of diuresis by means of isotopic tracer,electromagnetic flowmeter and ureter catheterization RESULTS:FHG could significantly increase the renal blood flow and glomerular filtration rate,and enhance the diuresis CONCLUSION:Its diuresis is based on the increase of rena l blood flow and glomerular filtration rate,which results in the decrease of ne phrotoxic substances such as blood urea nitrogen and serum creatinine