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The Expression and Significance of ICAM-1 on Myocardial Reperfusion Injury after Cardiac Transplantation in Rats / 中国医师杂志
Journal of Chinese Physician ; (12)2001.
Artículo en Chino | WPRIM | ID: wpr-521897
ABSTRACT
Objective To investigate the expression and significance of intercellular adhesion molecule-1 (ICAM-1) in graft reperfusion injury after cardiac transplantation in rats. Methods Twenty-four Wistar rats heterotopic cardiac transplantation models were randomly divided into control group (n=6) and experimental group (n=18). In control group, the ischemic period of the grafts was 60min without reperfusion. In experimental group, the grafts were respectively reperfused for 3h, 6h and 24h after 60min ischemic period. Immunohistochemical and biochemical techniques were used to detect myocardial ICAM-1 and myeloperoxidase (MPO). Results The expression of allograft ICAM-1 after reperfusion in experimental group was significantly higher than that in control group (P

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Chinese Physician Año: 2001 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Chinese Physician Año: 2001 Tipo del documento: Artículo