Application of bioinformatics in transcriptional regulation research / 中国病理生理杂志

ABSTRACT

Gene transcriptional regulation research is one of the major challenges in the post-genome era. Bioinformatics has become more important with the rapid accumulation of complete genome sequences and the advances of computational methods and related databases. The current computational approaches in promoter prediction, transcription factor binding site identification, composite elements prediction, co-regulation of gene expression analysis and phylogenetic footprinting in the regulatory region analysis are discussed in this review.