Effect of octreotide on pancreatic cancer cells transfected with SST 2 gene / 中国普通外科杂志
Chinese Journal of General Surgery
; (12)1997.
Article
en Zh
| WPRIM
| ID: wpr-522824
Biblioteca responsable:
WPRO
ABSTRACT
Objective To observe the effect of octreotide on human pancreatic cancer cells (PC-3) apoptosis after PC-3 transfected with somatostatin receptor type 2 (SST 2) gene. Methods SST 2 was transfected into PC-3 by liposome,the result of transfection was detected by immunohistochemistry. The apoptosis of PC-3 induced by using different dosage of octreotide were detected by MTT assay and flow cytometry. Results The effects of killing PC-3 by different dosage (0.2,0.4 and 0.8?g/ml ) of octreotide in transfected groups were significantly stronger than those in non-transfected groups(P
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of General Surgery
Año:
1997
Tipo del documento:
Article