Study on cell DNA damage induced by tetramine using comet assay / 中国法医学杂志
Chinese Journal of Forensic Medicine
;
(6)2002.
Artículo
en Chino
| WPRIM
| ID: wpr-523538
ABSTRACT
Objective To detect DNA damage in rat lymphocytes and brain cells induced by tetramine and study the toxicological mechanism of tetramine.Methods Lymphocytes and brain cells were separated and collected from healthy rats.DNA damages of cells which were exposed to various doses of tetramine for 60 min was detected using the single cell gel electrophoresis (SCGE) or comet assay.Results These are different degree DNA damages of lymphocytes and brain cells exposed from doses 1/20 LD 50 doses of tetramine to 1/2 LD 50 doses of tetramine.The test groups are very significantly statistical different to the control group(P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Forensic Medicine
Año:
2002
Tipo del documento:
Artículo
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