Influence of laminin on the expression of bcl-2 in rabbit cornea endothelial cells / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12)1989.
Article
en Zh
| WPRIM
| ID: wpr-525137
Biblioteca responsable:
WPRO
ABSTRACT
AIM: To investigate the influence of laminin (LN) on the expression of bcl-2 in rabbit cornea endothelial cells. METHODS: Cultured rabbit corneal endothelial cells were divided into three groups: normal control group, LN group and negative control group. Immunohistochemical technique and ELISA were used to measure the staining and A value to assess the levels of bcl-2 expression. RESULTS: Bcl-2 expression score showed that LN group had a strong positive expression. Control group only showed a weak expression. Negative control group showed a negative expression by immunohistochemical staining. The mean A value of each group were 1.21?0.18 (LN group), 1.05?0.14 (normal control group) and 0.04?0.01 (negative control group). CONCLUSION: LN promotes bcl-2 gene expression in rabbit cornea endothelial cells, and protects the cells from apoptosis.
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WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Pathophysiology
Año:
1989
Tipo del documento:
Article