Expression of TRAIL and TRAILR in human hepatocellular carcinoma and its therapeutic significance / 中国普通外科杂志
Chinese Journal of General Surgery
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-525482
ABSTRACT
Objective To evaluate the expression of tumor necrosis factor related apoptosis-inducing ligand (TRAIL) and its receptor(TRAILR) in human hepatocellular carcinoma (HCC), and its therapeutic potential for human HCC. Methods Expressions of TRAIL and TRAILR were determined in and adjacent to carcinoma tissues, and normal liver tissues. The cytotoxic effects of TRAIL in combination with chemotherapeutic agents on HCC cell lines were detected. Results Expression of TRAIL in tumor adjacent tissue was higher than in cancer tissue. There were high expression of DR and low expression of DcR in HCC tissue in contrast to normal hepatic tissue(?~ 2=4.68,P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of General Surgery
Año:
2001
Tipo del documento:
Artículo
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