Inflammation and coagulation activation are associated with gallstone formation in golden hamsters / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1999.
Artículo
en Chino
| WPRIM
| ID: wpr-525764
ABSTRACT
AIM:
To elucidate the relationship of inflammation, coagulation and cholesterol gallstone formation.METHODS:
Hamsters were divided into four groups control group (feeding normal diet), lithogenic diet (LD) 2 weeks group, LD 6 weeks group and LD+aspirin 6 weeks group. Gallstone incidence, antithrombin antigen (AT-ⅢAg), antithrombin activity (AT-ⅢAc), thrombin (F-ⅡaAc), plasminogen activator inhibitor activity (PAIAc), plasmin activity (PlmAc), D-dimerAg and C-reactive protein (CRP) in gallbladder bile were observed as read-out parameters.RESULTS:
The incidence of gallstones in control group, LD 2 weeks group, LD 6 weeks group and LD+aspirin group were 0%, 20%, 73% and 25%, respectively. AT-ⅢAg, F-ⅡaAc, D-dimer and CRP in LD 2 weeks group and LD 6 weeks group were significantly higher than those in the control group (P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Pathophysiology
Año:
1999
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS