Content Determination of Forsythin in Qingrejiedu Granules by HPLC / 中国药房

ABSTRACT

OBJECTIVE:To establish a HPLC method for content determination of forsythin in Qingrejiedu granules.ME_ THODSA Alltech Inersil ODS-2column(150mm?4.6mm,5?m)was used,the mobile phase was acetonitrile-water(18∶32), the detective wavelength was277nm,the column temperature was30℃,the flow rate was1.0ml/min.RESULTS:The linear range of forsythin was0.0984?g～12.3?g(r=0.9997),the average recovery was100.62%(RSD=0.6%).CONCLUSION:This method was easy to operate,good reproducibility and accurate result,it can be used for quality control in production Qin?grejiedu granules.