Expressions of nuclear factor-kappa B and monocyte chemoattractant protein-1 in renal tissue of uric acid nephropathy rats and their significance / 中国医师杂志
Journal of Chinese Physician
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-527797
ABSTRACT
Objective To investigate the role of nuclear factor-kappa B(NF-?B) and monocyte chemoattractant protein-1(MCP-1) in the pathogenesis of uric acid nephropathy.Methods Twenty male SD rats were divided into control group(group C) and model group(group M).The model rats with uric acid nephropathy were made using adenine.Immunohistochemistry was used to detect the expressions of NF-?B and MCP-1 in 18 days and the serum uric acid and renal fuction were measured respectively.Results In comparison with group C,the expressions of NF-?B and MCP-1 in the rats of group M were significantly increased(all P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
Journal of Chinese Physician
Año:
2001
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS