Effect of Dachengqi Decoction Combined with the Treatment Principle of Promoting Production of Body Fluid with Sweet-Flavored and Cold-natured drugs on the Earth-dry and Water-exhaust Syndrome / 中医杂志

ABSTRACT

Objective:To probe the mechanism of Dachengqi Decoction combined with the treatment principle of promoting production of body fluid with sweet-flavored and cold-natured drugs on the earth-dry and water-exhaust syndrome.Methods:Chinchilla Giganta rabbits were randomly divided into four groups,i.e. blank control group,pathological model group,timely purgation to preserve Yin treatment group and treatment group of purgation with drugs sweet in favor and cold in nature.Changes of symptoms,signs,pathological changes of organs,WBC count,nitric oxide(NO),superoxide dismutase(SOD),malondialdehyde(MDA),middle molecular substances(MMS),sulfydryl(-SH),K+ and Na+,and viscosities of whole blood and plasma before and after treatment were investigated.Results:There were significant differences in decrease of body temperature,increases of SOD,MMS,K+ and Na+,decreases of NO,MDA,-SH and viscosities of whole blood and plasma as the two treatment groups compared with the pathological model group(P