Accelerating hematopoietic recovery in mice after allogeneic bone marrow transplantation by co-infusion of bone marrow mesenchymal stem cells / 中国医师杂志
Journal of Chinese Physician
; (12)2001.
Article
en Zh
| WPRIM
| ID: wpr-528545
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WPRO
ABSTRACT
Objective To investigate the effect of co transfusion of bone marrow mesenchymal stem cells(BMMSC) on hematopoietic recovery in mice after allogeneic bone marrow transplantation(allo-BMT).Methods Both BMMSC obtained after three to four weeks of culture and bone marrow cells of donor mice C57BL/6(H-2~b) were transplanted into the recipient mice BalB/c(H-2~d) that were lethally irradiated.Peripheral blood cells were counted on day 1,7,and 14 post-transplantation.CFU-S in recipient bone marrows were measured on day 7 and 14.Results The numbers of peripheral WBC,RBC,platelets and the number of CFU-S in recipient bone marrows on day 7 and 14 were all significantly higher in the co-infusion group than those in control group(P
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Zh
Revista:
Journal of Chinese Physician
Año:
2001
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Article