The Effects of Transient Intensive Insulin Treatment on Beta-cell Function in Newly Diagnosed Type II Diabetic Patients / 昆明医科大学学报

ABSTRACT

11.1 mmol/L were treated by 2 weeks CSII.An intravenous glucose tolerance test(IVGTT) was performed before and after CSII.The levels of fasting plasma glucose(FPG),2 hours postprandial glucose(2hPG),glycosylated hemoglobin A1c(HbA1c),first-phase secretion of insulin,the mean area under the curve(AUC) of insulin,insulin sensitivity index(ISI),insulin resistance index(Homa IR) and insulin secretion index(Homa ?) were compared.Results The excellent control of FPG and 2hPG in 20 out of 21 patients were achieved stably in 2.8?1.6 days and 7.8?1.9 days by CSII.After the treatment,FPG,2h PG and HbA1c were significantly decreased(P