Technology Optimization and Identification of Ginkgo Biloba Extracts-hydroxyprop-?-cyclodextrin(GBE-HP-?-CD) Inclusion Compounds / 中国药房
China Pharmacy
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-530274
ABSTRACT
OBJECTIVE:
To optimize the preparation technology of Ginkgo biloba extracts-hydroxyprop-?-cyclodextrin(GBE-HP-?-CD) inclusion compounds and to identify this inclusion compound.METHODS:
The optimum preparation condition was studied by orthogonal test with encapsulation rate as the index of evaluation.The inclusion compounds were prepared with solution-agitating technique.The inclusion compounds were identified by phase solubility diagra-m,differential scanning calorimetry(DSC) and infrared spectroscopy methods,respectively.RESULTS:
The optimum inclusion condition was as followsthe ratio of GBE to HP-?-CD=1.5∶1;agitating time=6 h;inclusion temperature=50 ℃.CONCLUSION:
It has been preliminarily proved that it is possible for Ginkgo biloba extracts and hydroxyprop-?-cyclodextrin to be made into inclusion compounds.HP-?-CD has satisfactory solublization on Ginkgo biloba extracts.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
China Pharmacy
Año:
2001
Tipo del documento:
Artículo
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