Your browser doesn't support javascript.
loading
Protective effects of bone marrow mesenchymal stem cells against the renal tubular epithelial cell damage induced by cisplatin / 中国病理生理杂志
Chinese Journal of Pathophysiology ; (12)2000.
Artículo en Chino | WPRIM | ID: wpr-530816
ABSTRACT

AIM:

To investigate the protective effects and mechanism of mesenchymal stem cells on renal tubule cells treated by cisplatin.

METHODS:

The mesenchymal stem cells(MSCs)were separated from mouse bone marrow.The necrosis and apoptosis rate of renal tubule cells induced by cisplatin were detected by flow cytometry.After co-culture with MSCs,the above changes of renal tubule cells were detected.

RESULTS:

In co-culture system,the apoptotic rates of renal tubule cell were decreased obviously and the cell number increased obviously.

CONCLUSION:

The MSCs protect the renal tubule cells from apoptosis induced by cisplatin.This effect may be related with the paracrine effects of MSCs.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Pathophysiology Año: 2000 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Pathophysiology Año: 2000 Tipo del documento: Artículo