Your browser doesn't support javascript.
loading
Preparation and Encapsulation Efficiency Determination of Diclofenac Sodium Liposomes / 中国药房
China Pharmacy ; (12)2007.
Artículo en Chino | WPRIM | ID: wpr-531193
ABSTRACT

OBJECTIVE:

To prepare diclofenac sodium liposomes and establish a method for their quality control.

METHODS:

The diclofenac sodium liposomes were prepared by pH gradient method;the particle shape and size were measured by transmission electrical miscroscope;the concentration and encapsulation efficiency of diclofenac sodium in the liposomes were determined by HPLC.

RESULTS:

The prepared lipisomes were uniformly distributed with particle size of 150~175 nm.The linear range of diclofenac sodium was 0.01~1 mg?mL-1(r=0.999 0,n=6)at an average recovery of 100.05%(RSD=1.21%,n=6).The encapsulation efficiency ranged from 52.4% to 85.8%.

CONCLUSION:

High encapsulation efficiency of diclofenac sodium liposomes can be obtained from the established method.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: China Pharmacy Año: 2007 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: China Pharmacy Año: 2007 Tipo del documento: Artículo