Infrared spectroscopy characterization of normal and lung cancer cells originated from epithelium
Journal of Veterinary Science
;
: 299-304, 2009.
Artículo
en Inglés
| WPRIM
| ID: wpr-53250
ABSTRACT
The vibrational spectral differences of normal and lung cancer cells were studied for the development of effective cancer cell screening by means of attenuated total reflection infrared spectroscopy. The phosphate monoester symmetric stretching nus(PO3(2-)) band intensity at ~970 cm-1 and the phosphodiester symmetric stretching nus(PO2-) band intensity at ~1,085 cm-1 in nucleic acids and phospholipids appeared to be significantly strengthened in lung cancer cells with respect to the other vibrational bands compared to normal cells. This finding suggests that more extensive phosphorylation occur in cancer cells. These results demonstrate that lung cancer cells may be prescreened using infrared spectroscopy tools.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Espectrofotometría Infrarroja
/
Carcinoma
/
Mucosa Respiratoria
/
Línea Celular Tumoral
/
Células Epiteliales
/
Neoplasias Pulmonares
Límite:
Humanos
Idioma:
Inglés
Revista:
Journal of Veterinary Science
Año:
2009
Tipo del documento:
Artículo
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