The Cutoff Value of HbA1c in Predicting Diabetes in Korean Adults in a University Hospital in Seoul / 당뇨병
Korean Diabetes Journal
;
: 503-510, 2009.
Artículo
en Coreano
| WPRIM
| ID: wpr-53268
ABSTRACT
BACKGROUND:
Glycated hemoglobin (HbA1c) levels represent a 2~3 month average of blood glucose concentration. The use of HbA1c as a diagnostic tool for diabetes is gaining interest. Therefore, we determined the cutoff point of HbA1c for predicting abnormal glucose tolerance status in non-diabetic Korean subjects.METHODS:
We analyzed the data from 1,482 subjects without diabetes mellitus in whom a 75-g oral glucose tolerance test (OGTT) was performed due to suspected abnormal glucose tolerance. We obtained an HbA1c cutoff point for predicting diabetes using Receiver Operating Characteristic (ROC) curve analysis.RESULTS:
A cut-off point of 5.95% HbA1c yielded sensitivity of 60.8% and specificity of 85.6%, respectively, for predicting diabetes. There was a difference in HbA1c cut-off value between men and women, 5.85% and 6.05%, respectively.CONCLUSION:
To use the cut-off point of 5.95% HbA1c for predicting undiagnosed diabetes in Koreans may be reliable. However, studies of different ethnic groups have reported disparate HbA1c cut-off points. Thus, ethnicity, age, gender, and population prevalence of diabetes are important factors to consider in using elevated HbA1c value as a tool to diagnose diabetes.
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Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Glucemia
/
Hemoglobinas
/
Etnicidad
/
Prevalencia
/
Curva ROC
/
Sensibilidad y Especificidad
/
Diabetes Mellitus
/
Glucosa
/
Prueba de Tolerancia a la Glucosa
Tipo de estudio:
Estudio diagnóstico
/
Estudio de prevalencia
/
Estudio pronóstico
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Diabetes Journal
Año:
2009
Tipo del documento:
Artículo
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