The mRNA Expression of Different Muscle Fibre Types in Denervated Rat Musculus Cricoarytenoideus Posterior / 听力学及言语疾病杂志
Journal of Audiology and Speech Pathology
;
(6)2004.
Artículo
en Chino
| WPRIM
| ID: wpr-532812
ABSTRACT
Objective To investigate the expression of the mRNA of muscle fibre types in the denervated post cricoarytenoid(PCA)muscle of rat.Methods Unilateral recurrent laryngeal nerve of eight rats were removed.Eight rats were used as controls.The mRNA expression of heavy chain myosin of PCA muscle fibre subtypes was measured with real-time quantitative RT-PCR in control rats and denervated rats 40 days after denervation.Results Compared to the control group,there were no significantly differences in mRNA expression of each muscle subtype between two groups.The ratio of MyHC type I to IIB was increased significantly(P=0.018).Conclusion The increased ratio of MyHC subtype I to IIB suggests the decreased contraction power of denervated PCA muscle.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Audiology and Speech Pathology
Año:
2004
Tipo del documento:
Artículo
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