Attenuation Effect of Tianzhicao Capsules on Doxorubicin Induced Toxicity / 中国药房
China Pharmacy
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-533544
ABSTRACT
OBJECTIVE:
To search the attenuation action of Tianzhicao capsules on doxorubicin induced toxicity.METHODS:
Hepatoma H22 tumor-bearing mice were administrated with Tianzhicao capsules and doxorubicin orally.Then the growth of mice,changes in electrocardiogram (ECG),myocardial enzymes and myocardial morphological changes were determined after administration.RESULTS:
Tianzhicao capsules were not in synchronism with the action potential depolarization in ventricular muscle and cardiac injury induced by doxorubicin.Tianzhicao capsule also inhibited the increase of serum LHD and doxorubicin-induced cardiac injury.CONCLUSION:
Tianzhicao capsules show attenuation effect on doxorubicin-induced toxicity.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
China Pharmacy
Año:
2001
Tipo del documento:
Artículo
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