Efficacy Observation of Zhuanggu Huoxue Recipe for Necrosis of Femoral Head in Patients with Osteoporotic Femoral Neck Fracture / 中国药房

ABSTRACT

OBJECTIVE:To investigate the clinical efficacy of Zhuanggu huoxue recipe for necrosis of femoral head in patients with osteoporotic femoral neck fracture. METHODS:305 patients with osteoporotic femoral neck fracture randomized into therapy group and control group. Both groups were given internal fixation therapy and continuous traction treatment for skin. Therapy group were given Zhuanggu huoxue decoction (p.o. b.i.d) for 12 weeks. Control group were given ossotide and puerarin. At 1st month,2nd month,4th month,6th month,12th month,18th month after operation,roentgenograms of bone in femoral lateral position were taken to observe the fracture healing and the occurrence of femoral head necrosis. At 4th month,6th month,8th month after radiotherapy,MRI of double lateral hip was taken to observe the occurrence of femoral head necrosis. RESULTS:The rate of femoral head necrosis and nonunion of fracture in therapy group were all lower than in control group (P