Clinical Manifestation and Preventive Measures of ADR Induced by Shengmai Injection / 中国药房

ABSTRACT

OBJECTIVE:To explore the situation and relevant factors of ADR induced by Shengmai injection and find out reason and preventive measure of ADR in order to provide reference for rational use of drugs. METHODS:60 ADR cases of Shengmai injection published from 1989 to 2009 were analyzed in terms of age distribution,organs and systems involved in ADR and its manifestation. RESULTS:ADR cases induced by Shengmai injection mainly were allergic reactions(including rash,urticaria,conjunctival edema,fever,chills,allergic shock),34 cases accounting for 56.67%,followed by gastrointestinal system,7 cases accounting for 11.67%.7 cases of cardiovascular system accounted for 11.67%,other manifested as cardiovascular system response, visual impairment and local pain,etc.CONCLUSION:Clinical staff should be aware of the characteristics of ADR induced by Shengmai injection and its pathogenesis and grasp medication time as well as preventive measures. Drug use should be standardized to avoid and decrease the incidence of ADR.