Systematic Review of Clinical Efficacy of Amlodipine in the Treatment of Variant Angina / 中国药房
China Pharmacy
;
(12)2005.
Artículo
en Chino
| WPRIM
| ID: wpr-534243
ABSTRACT
OBJECTIVE:
To evaluate the clinical efficacy of amlodipine in treatment of vasospastic angina systematically.METHODS:
Literatures were retrieved from MEDLINE,EMBASE,CNKI,CBM and Wanfang database,etc.Data of literatures were analyzed using RevMan 4.2 software.RESULTS:
3 RCTs were included in meta-analysis and 1 RCT was involved in descriptive analysis.Compared with diltiazem,amlodipine was similar to benidipine in reducing the incidence of cardiovascular events;there was no statistical significance[OR=0.79,95%CI(0.57,1.10),P=0.16].Effective rate of amlodipine was significantly higher than isosorbide dinitrate,there were statistical significance[OR=7.33,95%CI(1.47,36.66),P=0.02].Compared with placebo,amlodipine could reduce occurrence times of angina significantly.CONCLUSION:
Amlodipine is effective in treatment of vasospastic angina and can reduce the incidence of cardiovascular events in patients with vasospastic angina.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Ensayo Clínico Controlado
/
Revisiones Sistemáticas Evaluadas
Idioma:
Chino
Revista:
China Pharmacy
Año:
2005
Tipo del documento:
Artículo
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