Analysis of 302 ADR Cases Caused by Danshen Injection / 中国药房

ABSTRACT

OBJECTIVE: To analyze the types and the potential causes of Danshen injection inducing ADR cases. METHODS: 302 ADR cases induced by Danshen injection were collected from ADR cases reported in Jiangsu province from 2003 to 2008 according to reported primarily susceptive drug and the description of the ADR. All cases were analyzed statistically to find out possible reason that ADR was induced by active components of Danshen injection. RESULTS: Of total 302 ADR cases, 0.66% was likely to be caused by the active components of Danshen injection; 96.36% allergic reaction were not possibly related to active components; 2.32% was caused by the drug preparation; 0.66% was caused by unclear reason. CONCLUSION: More than 90% ADR cases induced by Danshen injection manifests as allergic reaction, which isn’t possibly related to main active components. The active components could induce the hemorrhage.